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Buy Calicheamicin y1 powder for research only

所属类别:Inhibitors 点击次数:736次 发布时间:2017-05-18

Calicheamicin y1 powder
详情
 Calicheamicin y1 Basic Info.
Calicheamicin
CAS:108212-75-5
MF:C55H74IN3O21S4
MW:1368.35000
LogP:4.36950
PSA:409.64000
The calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, with calicheamicin γ1 being the most notable. It was isolated originally in the mid-1980s from the chalky soil, or "calichi pits", located in Kerrville, Texas. The sample was collected by a scientist working for Lederle Labs. It is extremely toxic to all cells and, in 2000, a CD33 antigen-targeted immunoconjugate N-acetyl dimethyl hydrazide calicheamicin was developed and marketed as targeted therapy against the non-solid tumor cancer acute myeloid leukemia (AML).Calicheamicin γ1 and the related enediyne esperamicin are the two of the most potent antitumor agents known.
 

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