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Tretinoin Home您现在的位置:HOME >> PRODUCTS >> Medicine Active ingredient

Tretinoin

所属类别:Medicine Active ingredient 点击次数:385次 发布时间:2017-04-13

Tretinoin
详情
 Tretinoin Basic Info.
Synonyms:  TRETINOIN VITAMIN A ACID;TRANS-RETINOIC ACID;TRANS VITAMIN A ACID;VITAMIN A ACID;RETINOIC ACID
CAS:     302-79-4
MF:     C20H28O2
MW:     300.44
EINECS:     206-129-0
mp:      180-181 °C(lit.)
storage temp: 2-8°C
Water Solubility: insoluble
Appearance: yellow powder
 
Medical uses:
 
Skin use 
Tretinoin is most commonly used to treat acne.  It is also used off-label to treat and reduce the appearance of stretch marks by increasing collagen production in the dermis. 
In topical form, this drug is pregnancy category C and should not be used by pregnant women. 
People using the topical form should not also use any cream or lotion that has a strong drying effect, contains alcohol, astringents, spices, lime, sulfur, , or aspirin, as these may interact with tretinoin or exacerbate its side effects. 
 
Leukemia 
Tretinoin is used to induce remission in people with acute promyelocytic leukemia who have a mutation (the t(15;17) translocation 160 and/or the presence of the PML/RARα gene) and who don't respond toanthracyclines or can't take that class of drug. It is not used for maintenance therapy. 
In oral form, this drug is pregnancy category D and should not be used by pregnant women as it may harm the fetus.

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