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Terlipressin Home您现在的位置:HOME >> PRODUCTS >> Peptides

Terlipressin

所属类别:Peptides 点击次数:459次 发布时间:2017-04-12

Terlipressin
详情
 Terlipressin is an analogue of vasopressin used as a vasoactive growth hormone peptides drug in the management of hypotension .
 
Terlipressin Acetate,Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome .Terlipressin is growth hormone peptides . In addition , it is used to treat bleeding esophageal varices .
 
Terlipressin Acetate,Between the patients with cirrhosis of the liver into the portal circulation of each vein and venous congestion can occur in vascular anastomosis , portal vein pressure rise phenomenon . The most frequently appeared in the azygos vein anastomosis with lower esophageal varices , instant tube .
 
Teriparatide acetate Basic Info.
Product Name : Teriparatide Acetate/Forteo/52232-67-4
Appearance :White powder
Product Name: Terlipressin Acetate 
Cas No.: 14636-12-5
Molecular Formula: C52H74N16O15S2
Molecular Weight: 1227.37
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%):  ≥80.0% 
Water Content(Karl Fischer): ≤10.0%
Specific Rotation (20/D): -95.0~-105.0°(c=1 1%HAc)
Acetate Content (HPIC): ≤15.0%
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
 
 
 
Introduction :
Teriparatide is a recombinant form of parathyroid hormone. It is an effective anabolic (i.e., bone growing) agent[1] used in the treatment of some forms of osteoporosis.It is also occasionally used off-label to speed fracture healing. Teriparatide is identical to a portion of human parathyroid hormone (PTH) and intermittent use activates osteoblasts more than osteoclasts, which leads to an overall increase in bone.
Description:
 
Terlipressin (trade names Teripress by New Medicon Pharma and Glypressin by Ferring Pharmaceuticals) is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.
Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.
Between the patients with cirrhosis of the liver into the portal circulation of each vein and venous congestion can occur in vascular anastomosis, portal vein pressure rise phenomenon. The most frequently appeared in the azygos vein anastomosis with lower esophageal varices, instant tube.
 
Application:
 
This product is pressurized prodrug hormone, vasopressin glycyl in injection into the blood after enzymatic hydrolysis in the molecule is produced a continuous low level. The portal venous pressure it generates the desired effect, but the changes of arterial blood pressure than the use of vasopressin after much smaller, and the blood of a few do not increase the fibrinolytic. Push once its role can be maintained for about 4 ~ 6h.
Intravenous injection, 2mg, every 4 ~ 6h again, until the control, use at most 24h. It is not for children.
 
 
 

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