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Sermorelin Home您现在的位置:HOME >> PRODUCTS >> Peptides

Sermorelin

所属类别:Peptides 点击次数:345次 发布时间:2017-04-12

Sermorelin
详情
Great White Powder Peptides Sermorelin (2mg/vial) To Gain Muscle
 
Sermorelin acetate is a recently synthesized (man-made) peptide analogue of growth hormone releasing hormone (GHRH) a naturally occurring hormone that is produced in the hypothalamus and stimulates and controls the production of growth hormone (GH) within the pituitary gland. GHRH, which is necessary for growth and development, was first described by Nobel Laureates R. Guilleman and A Shalley. In the 1970s one of their students, William Wehrenberg, began studying which part of the GHRH molecule was essential in stimulating the pituitary gland.
 
By removing individual amino acids from the GHRH molecule, Wehrenberg found that only the first 29 amino acids were essential for the stimulation of GH production in the pituitary gland. Semorelin is therefore only comprised of these 29 essential amino acids, forming a short polypeptide chain that is considered one of the shortest functional fragments of the GHRH molecule. It was first developed with a one-step chromatographic method capable of separating all isomers of polyethylene glycol (PEG) from naturally occurring GHRH.
 
Sermorelin: 
CAS NO.: 86168-78-7
Molecular Formula: C149H246N44O42S
Peptide purity: 98.0% min. 
Appearance: White lyophilized powder
Place of Origin: China
Standard: USP
Certification: SGS
Method of Analysis: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.
 
 
Description: 
Sermorelin is now used as a standard test for growth hormone secretion and is primarily prescribed for children who do not produce GH properly and fail to grow healthily as a result. It has a secondary, off-label use in "repairing" declining GH levels (a natural side effect of aging that leads to weight gain, decreased strength and muscle mass, and insomnia in elder subjects). GH levels typically peak at around 20 years of age in humans and fall by about 14% for every decade that passes, but use of Sermorelin can potentially rejuvenate GH back to youthful levels. 
 
Hexarelin (Hexarelin Acetate) is chemically designed as L-Histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide. Hexarelin (Hexarelin Acetate) is a potent GHRP-6 analog,
whose structure (His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2) creates a greater stability than GHRP-6 due to a substituted (2 Me)Trp. Hexarelin has a half-life of about 70 min, longer than that of GHRP-6. Replacement of the naturally occurring L-amino acids for the D-configuration results in these longer
half-lives.
 
Hexarelin has shown that it is highly stimulated at 30 minutes after being induced by rapid and sustained GH secretion. The pituitary gland produces GH in the brain, in children this hormone helps them to grow and in adults it helps to maintain muscle and burn fat. In one sixteen-week study, it has been shown that GH levels return to normal after stopping use after four weeks.
 
Benefits of Sermorelin:
 
These are detailed below:
1. Changes in Body Composition Human Growth Hormone Stimulators
Changes in body composition due to decreasing levels of Human Growth Hormone are reflected by a decrease in lean body mass (muscle) and an increase in fat mass. Correcting Human Growth Hormone levels has been shown to reverse this state by improving muscle mass and reducing fat.
 
2. Bone Mineral Density
Research indicates that Human Growth Hormone deficiency in adults contributes to a reduction in bone density and therefore increased risk of osteoporosis. It has also been shown that Human Growth Hormone replacement therapy for greater than 12 months results in improved bone mineral density and hence, lower risk of osteoporosis.
 
3. Muscle Strength
Due to changes in body composition detailed above, muscle strength is understandably compromised. As Human Growth Hormone therapy corrects body composition and improves muscle mass, muscle strength also improves. The best results are gained after 12 months of Human Growth Hormone therapy.
 
4. Joint Health
By improving bone mineral density and increasing muscle mass and strength, Human Growth Hormone therapy can help to prevent joint deterioration that is a feature of arthritis. Optimal growth hormone levels are also essential for health of connective tissue such as the synovium found in joints.
 
5. Exercise Performance
Exercise performance is reduced in individuals with growth hormone deficiency. This appears to be partially due to reductions in bone density and muscle mass but also in part due to a reduction in oxygen uptake. Human Growth Hormone therapy for 6 months has been shown to improve exercise performance by improving muscle mass and also oxygen uptake. 


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